When is a blood and marrow transplant (stem cell transplant) used for MDS-related anemia?

MDS experts, Dr Rafael Bejar and Dr Casey O’Connell describe when a blood and marrow (stem cell transplant) is used for MDS-related anemia. Although stem cell transplantation represents the only cure for MDS, it is not a guarantee and the process is associated with a lot of risks. The decision to proceed with a transplant is a complicated one involving several considerations, including age, MDS risk category, and presence of co-existing diseases. Stem cell transplantation is often considered for people with high risk disease. On average, lower risk MDS patients will likely do better living with their disease and taking non-transplant treatments, rather than undergoing a stem cell transplant.

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Animation - Managing and Treating MDS-related Anemia
1. Animation - Managing and Treating MDS-related Anemia
Slide Show - Managing and Treating MDS-related Anemia
2. Slide Show - Managing and Treating MDS-related Anemia

Expert Videos

What are the treatment options for MDS-related anemia?
3. What are the treatment options for MDS-related anemia?
What are the goals of treatment for MDS-related anemia?
4. What are the goals of treatment for MDS-related anemia?
How is higher-risk MDS-related anemia treated?
5. How is higher-risk MDS-related anemia treated?
What is “refractory anemia” and “primary anemia”? Are these terms still in use?
6. What is “refractory anemia” and “primary anemia”? Are these terms still in use?
When do people with MDS-related anemia need blood transfusions?
7. When do people with MDS-related anemia need blood transfusions?
How often could I need a blood transfusion for MDS-related anemia?
8. How often could I need a blood transfusion for MDS-related anemia?
Are blood transfusions safe? Are there risks?
9. Are blood transfusions safe? Are there risks?
What is iron overload, and how it is treated?
10. What is iron overload, and how it is treated?
Can my bone marrow return to normal and produce its own red blood cells?
11. Can my bone marrow return to normal and produce its own red blood cells?
What new treatments are in development for MDS-related anemia?
12. What new treatments are in development for MDS-related anemia?
Are there clinical trials for MDS-related anemia? What does the future hold?
13. Are there clinical trials for MDS-related anemia? What does the future hold?
What treatment questions should I ask my doctor about my MDS?
14. What treatment questions should I ask my doctor about my MDS?
When is a blood and marrow transplant (stem cell transplant) used for MDS-related anemia?
15. When is a blood and marrow transplant (stem cell transplant) used for MDS-related anemia?

Patient Videos

Abby’s story: What has been the biggest challenge with your MDS-related anemia?
16. Abby’s story: What has been the biggest challenge with your MDS-related anemia?
Barry’s story: What has been the biggest challenge with your MDS-related anemia?
17. Barry’s story: What has been the biggest challenge with your MDS-related anemia?
Bill’s story: What has been the biggest challenge with your MDS-related anemia?
18. Bill’s story: What has been the biggest challenge with your MDS-related anemia?
Abby’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
19. Abby’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
Barry’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
20. Barry’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
Bill’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
21. Bill’s story: What has been the greatest success and greatest challenge with your MDS-related Anemia treatment?
Abby’s story: What advice do you have for other patients on their journey with MDS-related anemia?
22. Abby’s story: What advice do you have for other patients on their journey with MDS-related anemia?
Barry’s story: What advice do you have for other patients on their journey with MDS-related anemia?
23. Barry’s story: What advice do you have for other patients on their journey with MDS-related anemia?
Bill’s story: What advice do you have for other patients on their journey with MDS-related anemia?
24. Bill’s story: What advice do you have for other patients on their journey with MDS-related anemia?

This educational activity has been developed by
the Myelodysplastic Syndromes Foundation, Inc and Mechanisms in Medicine Inc.

This activity is supported by an educational grant from Acceleron Pharma, Celgene Corporation, Jazz Pharmaceuticals, Novartis, and Takeda Oncology.

This website is part of the Animated Patient™ series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.